Article
Toll like receptor 3 & 4 responses of human turbinate derived mesenchymal stem cells: stimulation by double stranded RNA and lipopolysaccharide.
PloS one - 1 Jan 2014
Hwang Se Hwan, Cho Hye Kyung, Park Sang Hi, Lee WeonSun, Lee Hee Jin, Lee Dong Chang, Oh Jeong Hoon, Park Sun Hwa, Kim Tai-Gyu, Sohn Hyun-Jung, Kang Jun Myung, Kim Sung Won
Abstract excerpt
BACKGROUND AND OBJECTIVES: Multipotent mesenchymal stromal cells (MSCs) represent a promising cell-based therapy for a number of inflammatory or autoimmune diseases. Herein, Toll like receptor (TLR) expression by MSCs and their immune regulatory roles are investigated. In this study, we investigated the influence of TLR on the immune response, proliferation, and differentiation potential of human turbinated MSC...
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