Article
Development of a melanoma risk prediction model incorporating MC1R genotype and indoor tanning exposure: impact of mole phenotype on model performance.
PloS one - 1 Jan 2014
Penn Lauren A, Qian Meng, Zhang Enhan, Ng Elise, Shao Yongzhao, Berwick Marianne, Lazovich DeAnn, Polsky David
Abstract excerpt
BACKGROUND: Identifying individuals at increased risk for melanoma could potentially improve public health through targeted surveillance and early detection. Studies have separately demonstrated significant associations between melanoma risk, melanocortin receptor (MC1R) polymorphisms, and indoor ultraviolet light (UV) exposure. Existing melanoma risk prediction models do not include these factors; therefore, we...
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