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Article

Behavioral and neuroanatomical abnormalities in pleiotrophin knockout mice.

PloS one - 1 Jan 2014

Krellman Jason W, Ruiz Henry H, Marciano Veronica A, Mondrow Bracha, Croll Susan D

Abstract excerpt

Pleiotrophin (PTN) is an extracellular matrix-associated protein with neurotrophic and neuroprotective effects that is involved in a variety of neurodevelopmental processes. Data regarding the cognitive-behavioral and neuroanatomical phenotype of pleiotrophin knockout (KO) mice is limited. The purpose of this study was to more fully characterize this phenotype, with emphasis on the domains of learning and memory,...

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Identifiers

PMID: 25000129
DOI: 10.1371/journal.pone.0100597
PMCID: PMC4085064

Genes

PTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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