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Article

Unforeseen Consequences of Excluding Missing Data from Next-Generation Sequences: Simulation Study of RAD Sequences.

Systematic biology - 1 May 2016

Huang Huateng, Knowles L Lacey

Abstract excerpt

There is a lack of consensus on how next-generation sequence (NGS) data should be considered for phylogenetic and phylogeographic estimates, with some studies excluding loci with missing data, whereas others include them, even when sequences are missing from a large number of individuals. Here, we use simulations, focusing specifically on RAD (Restriction site Associated DNA) sequences, to highlight some of the...

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PMID: 24996413
DOI: 10.1093/sysbio/syu046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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