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Article

Mutations as missing data: inferences on the ages and distributions of nonsynonymous and synonymous mutations.

Genetics - 1 Sept 2001

Nielsen R

Abstract excerpt

This article describes a new Markov chain Monte Carlo (MCMC) method applicable to DNA sequence data, which treats mutations in the genealogy as missing data. The method facilitates inferences regarding the age and identity of specific mutations while taking the full complexities of the mutational process in DNA sequences into account. We demonstrate the utility of the method in three applications. First, we...

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Identifiers

PMID: 11560914
DOI: 10.1093/genetics/159.1.401
PMCID: PMC1461805

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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