Article
Polymorphisms at newly identified lipid-associated loci are associated with blood lipids and cardiovascular disease in an Asian Malay population.
Journal of lipid research - 1 Mar 2009
Tai E Shyong, Sim Xue Ling, Ong Twee Hee, Wong Tien Yin, Saw Seang Mei, Aung Tin, Kathiresan Sekar, Orho-Melander Marju, Ordovas Jose M, Tan Jonathan T, Seielstad Mark
Abstract excerpt
We conducted a cross-sectional study of Malay participants aged 40-80 years (n = 2,932) to examine the associations between polymorphisms at newly identified, lipid-associated loci with blood lipid levels and prevalent cardiovascular disease (CVD) in a Malay population in Asia. A polymorphism adjacent to the TRIB1 locus (rs17321515) was associated with elevated total cholesterol and LDL-cholesterol (LDL-C) after...
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