Article
Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replication.
Circulation. Cardiovascular genetics - 1 Oct 2008
Chasman Daniel I, Paré Guillaume, Zee Robert Y L, Parker Alex N, Cook Nancy R, Buring Julie E, Kwiatkowski David J, Rose Lynda M, Smith Joshua D, Williams Paul T, Rieder Mark J, Rotter Jerome I, Nickerson Deborah A, Krauss Ronald M, Miletich Joseph P, Ridker Paul M
Abstract excerpt
BACKGROUND: Genome-wide genetic association analysis represents an opportunity for a comprehensive survey of the genes governing lipid metabolism, potentially revealing new insights or even therapeutic strategies for cardiovascular disease and related metabolic disorders. METHODS AND RESULTS: We have performed large-scale, genome-wide genetic analysis among 6382 white women with replication in 2 cohorts of 970...
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