Article
Finding consensus stable local optimal structures for aligned RNA sequences and its application to discovering riboswitch elements.
International journal of bioinformatics research and applications - 1 Jan 2014
Li Yuan, Zhong Cuncong, Zhang Shaojie
Abstract excerpt
Many non-coding RNAs (ncRNAs) can fold into alternate native structures and perform different biological functions. The computational prediction of an ncRNA's alternate native structures can be conducted by analysing the ncRNA's energy landscape. Previously, we have developed a computational approach, RNASLOpt, to predict alternate native structures for a single RNA. In this paper, in order to improve the...
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