Article
Simulated annealing based algorithm for identifying mutated driver pathways in cancer.
BioMed research international - 1 Jan 2014
Li Hai-Tao, Zhang Yu-Lang, Zheng Chun-Hou, Wang Hong-Qiang
Abstract excerpt
With the development of next-generation DNA sequencing technologies, large-scale cancer genomics projects can be implemented to help researchers to identify driver genes, driver mutations, and driver pathways, which promote cancer proliferation in large numbers of cancer patients. Hence, one of the remaining challenges is to distinguish functional mutations vital for cancer development, and filter out the...
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