Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell cycle dependent oscillatory expression of estrogen receptor-α links Pol II elongation to neoplastic transformation.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jul 2014

Vantaggiato Cristina, Tocchetti Marta, Cappelletti Vera, Gurtner Aymone, Villa Alessandro, Daidone Maria Grazia, Piaggio Giulia, Maggi Adriana, Ciana Paolo

Abstract excerpt

Decades of studies provided a detailed view of the mechanism of estrogen receptor-α (ERα) regulated gene transcription and the physio-pathological relevance of the genetic programs controlled by this receptor in a variety of tissues. However, still limited is our knowledge on the regulation of ERα synthesis. Preliminary observations showed that the expression of ERα is cell cycle regulated. Here, we have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Cell Cycle

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromatin Immunoprecipitation

Share to Estrogen Receptor alpha

Share to MCF-7 Cells

Share to Proto-Oncogene Mas

Share to Real-Time Polymerase Chain Reaction

Share to RNA Polymerase II

Source

Open in PubMed Open full text

Identifiers

PMID: 24979764
DOI: 10.1073/pnas.1321750111
PMCID: PMC4084491

Genes

MYB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell cycle dependent oscillatory expression of estrogen receptor-α links Pol II elongation to neoplastic transformation.PMID 24979764Read ↗

Association of PvuII and XbaI polymorphisms on estrogen receptor alpha (ESR1) gene to changes into serum lipid profile of post-menopausal women: Effects of aging, body mass index and breast cancer incidence.Semantic proximity Read ↗

Genetic polymorphims of estrogen receptor alpha -397 PvuII (T>C) and -351 XbaI (A>G) in a portuguese population: prevalence and relation with breast cancer susceptibility.Semantic proximity Read ↗

Association of ESRα-Pvull and ESRα-Xbal Polymorphisms with Breast Cancer Susceptibility in an Iranian Population: A Hospital-Based Case-Control Study.Semantic proximity Read ↗

The estrogen receptor alpha gene and breast cancer risk (The Netherlands).Semantic proximity Read ↗

[Puvll and Xbal gene polymorphisms of estrogen receptor alpha in children and young adults with cancer from north-eastern region of Poland].Semantic proximity Read ↗

Menopausal status modifies breast cancer risk associated with ESR1 PvuII and XbaI polymorphisms in Asian women: a HuGE review and meta-analysis.Semantic proximity Read ↗

Estrogen receptor alpha (ERS1) SNPs c454-397T>C (PvuII) and c454-351A>G (XbaI) are risk biomarkers for breast cancer development.Semantic proximity Read ↗

Prevalence of ERα-397 PvuII C/T, ERα-351 XbaI A/G and PGR PROGINS polymorphisms in Brazilian breast cancer-unaffected women.Semantic proximity Read ↗

Estrogen receptor alpha gene polymorphisms and risk of prostate cancer: a meta-analysis involving 18 studies.Semantic proximity Read ↗

<i>DNA polymerase</i> θ up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instabilitySemantic proximity Read ↗

Minireview: Genomic Organization of the Human ERα Gene Promoter RegionSemantic proximity Read ↗

DNA polymerase β deficiency is linked to aggressive breast cancer: A comprehensive analysis of gene copy number, mRNA and protein expression in multiple cohortsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.