Article
Prevalence of ERα-397 PvuII C/T, ERα-351 XbaI A/G and PGR PROGINS polymorphisms in Brazilian breast cancer-unaffected women.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Oct 2012
Giacomazzi J, Aguiar E, Palmero E I, Schmidt A V, Skonieski G, Filho D D, Bock H, Saraiva-Pereira M L, Ewald I P, Schuler-Faccini L, Camey S A, Caleffi M, Giugliani R, Ashton-Prolla P
Abstract excerpt
Polymorphisms of hormone receptor genes have been linked to modifications in reproductive factors and to an increased risk of breast cancer (BC). In the present study, we have determined the allelic and genotypic frequencies of the ERα-397 PvuII C/T, ERα-351 XbaI A/G and PGR PROGINS polymorphisms and investigated their relationship with mammographic density, body mass index (BMI) and other risk factors for BC. A...
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