Article
Phenotypic characterization of miR-92a-/- mice reveals an important function of miR-92a in skeletal development.
PloS one - 1 Jan 2014
Penzkofer Daniela, Bonauer Angelika, Fischer Ariane, Tups Alexander, Brandes Ralf P, Zeiher Andreas M, Dimmeler Stefanie
Abstract excerpt
MicroRNAs (miRNAs, miRs) emerged as key regulators of gene expression. Germline hemizygous deletion of the gene that encodes the miR-17∼92 miRNA cluster was associated with microcephaly, short stature and digital abnormalities in humans. Mice deficient for the miR-17∼92 cluster phenocopy several...
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