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Neuroimaging in Huntington’s disease

1 Jan 2014

Abstract excerpt

Huntington's disease (HD) is a progressive and fatal neurodegenerative disorder caused by an expanded trinucleotide CAG sequence in huntingtin gene (HTT) on chromosome 4. HD manifests with chorea, cognitive and psychiatric symptoms. Although advances in genetics allow identification of individuals carrying the HD gene, much is still unknown about the mechanisms underlying the development of overt clinical...

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PMID: 24976932
DOI: 10.4329/wjr.v6.i6.301

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