Article
Sequence heterogeneity of NS5A and core proteins of hepatitis C virus and virological responses to pegylated-interferon/ribavirin combination therapy.
Microbiology and immunology - 1 Jun 2011
El-Shamy Ahmed, Shoji Ikuo, Saito Takafumi, Watanabe Hisayoshi, Ide Yoshi-Hiro, Deng Lin, Kawata Sumio, Hotta Hak
Abstract excerpt
Both host and viral factors have been implicated in influencing the response to pegylated-interferon/ribavirin (PEG-IFN/RBV) therapy for hepatitis C virus (HCV) infection. Among the viral factors, sequence heterogeneity within NS5A and core regions has been proposed. This study aimed to clarify the relationship between virological responses to PEG-IFN/RBV therapy and sequence heterogeneity within NS5A, including...
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