Article
Engineering of Saccharomyces cerevisiae for the accumulation of high amounts of triacylglycerol.
Microbial cell factories - 27 Jul 2021
Arhar Simon, Gogg-Fassolter Gabriela, Ogrizović Mojca, Pačnik Klavdija, Schwaiger Katharina, Žganjar Mia, Petrovič Uroš, Natter Klaus
Abstract excerpt
BACKGROUND: Fatty acid-based substances play an important role in many products, from food supplements to pharmaceutical products and biofuels. The production of fatty acids, mainly in their esterified form as triacylglycerol (TAG), has been intensively studied in oleaginous yeasts, whereas much less effort has been invested into non-oleaginous species. In the present work, we engineered the model yeast...
Topics
- Biofuels
- Biomass
- Culture Media
- Diacylglycerol O-Acyltransferase
- Fatty Acids
- Glycogen
- Metabolic Engineering
- Mutation
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Triglycerides