Article
PON1 Q192R polymorphism (rs662) is associated with childhood embryonal tumors.
Molecular biology reports - 1 Sept 2014
Vasconcelos Gisele M, Gonçalves Bruno Aguiar Alves, Montalvão-de-Azevedo Rafaela, Thuler Luiz Claúdio Santos, Braga Flavio Henrique Paraguassu, Pombo-de-Oliveira Maria S, de Camargo Beatriz
Abstract excerpt
Genetic susceptibility and environment exposures are associated risk factors in carcinogenesis. Gene polymorphisms that decrease the activity of detoxifying carcinogen substances may modify the effect of exposures. We investigated whether the polymorphisms PON1 rs662 (Q192R), and PON1 rs854560 (L55M) would be associated with embryonal tumors in Brazilian children. Blood samples from 163 children with embryonal...
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