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Article

Association of novel polymorphisms in TMEM39A gene with systemic lupus erythematosus in a Chinese Han population.

BMC medical genetics - 20 Apr 2017

Cai Xinze, Huang Wenyue, Liu Xudong, Wang Lining, Jiang Yi

Abstract excerpt

BACKGROUND: This study aimed to assess the association between 14 single nucleotide polymorphisms (SNPs) in six genes (IRF8, TMEM39A, IKZF3, ORMDL3, GSDMB, and ZPBP2) and systemic lupus erythematosus (SLE) in a Chinese Han population sample. METHODS: We carried out a case-control study of 415 patients with SLE and 470 healthy controls without autoimmune disease or cancer. DNA for genetic analysis was isolated...

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Identifiers

PMID: 28427360
DOI: 10.1186/s12881-017-0405-8
PMCID: PMC5399404

Genes

GSDMB
IKZF3
ORMDL3
ZPBP2

Provenance

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