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Article

Driver somatic mutations identify distinct disease entities within myeloid neoplasms with myelodysplasia.

Blood - 28 Aug 2014

Malcovati Luca, Papaemmanuil Elli, Ambaglio Ilaria, Elena Chiara, Gallì Anna, Della Porta Matteo G, Travaglino Erica, Pietra Daniela, Pascutto Cristiana, Ubezio Marta, Bono Elisa, Da Vià Matteo C, Brisci Angela, Bruno Francesca, Cremonesi Laura, Ferrari Maurizio, Boveri Emanuela, Invernizzi Rosangela, Campbell Peter J, Cazzola Mario

Abstract excerpt

Our knowledge of the genetic basis of myelodysplastic syndromes (MDS) and myelodysplastic/myeloproliferative neoplasms (MDS/MPN) has considerably improved. To define genotype/phenotype relationships of clinical relevance, we studied 308 patients with MDS, MDS/MPN, or acute myeloid leukemia evolving from MDS. Unsupervised statistical analysis, including the World Health Organization classification criteria and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Core Binding Factor Alpha 2 Subunit

Share to Hematologic Neoplasms

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Source

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Identifiers

PMID: 24970933
DOI: 10.1182/blood-2014-03-560227
PMCID: PMC4148773

Genes

SRSF2
TET2

Provenance

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