Genomic Landscape of Myelodysplastic/Myeloproliferative Neoplasms: A Multi-Central Study.

doi:10.3390/ijms251810214

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Genomic Landscape of Myelodysplastic/Myeloproliferative Neoplasms: A Multi-Central Study.

International journal of molecular sciences - 23 Sept 2024

Fei Fei, Jariwala Amar, Pullarkat Sheeja, Loo Eric, Liu Yan, Tizro Parastou, Ali Haris, Otoukesh Salman, Amanam Idoroenyi, Artz Andrew, Ally Feras, Telatar Milhan, Nakamura Ryotaro, Marcucci Guido, Afkhami Michelle

Abstract excerpt

The accurate diagnosis and classification of myelodysplastic/myeloproliferative neoplasm (MDS/MPN) are challenging due to the overlapping pathological and molecular features of myelodysplastic syndrome (MDS) and myeloproliferative neoplasm (MPN). We investigated the genomic landscape in different MDS/MPN subtypes, including chronic myelomonocytic leukemia (CMML; n = 97), atypical chronic myeloid leukemia (aCML; n...

Topics

Humans
Aged
Male
Female
Middle Aged
Mutation
Myelodysplastic-Myeloproliferative Diseases
Aged, 80 and over
Proto-Oncogene Proteins
Adult

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Dioxygenases

Serine-Arginine Splicing Factors

Janus Kinase 2

DNA-Binding Proteins

Genomics

Leukemia, Myelomonocytic, Chronic

Myelodysplastic Syndromes

Core Binding Factor Alpha 2 Subunit

Source

Open in PubMed Open full text

Identifiers

PMID: 39337700
DOI: 10.3390/ijms251810214
PMCID: PMC11431978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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