Article
Arx together with FoxA2, regulates Shh floor plate expression.
Developmental biology - 1 Sept 2014
Cho Ginam, Lim Youngshin, Cho Il-Taeg, Simonet Jacqueline C, Golden Jeffrey A
Abstract excerpt
Mutations in the Aristaless related homeodomain transcription factor (ARX) are associated with a diverse set of X-linked mental retardation and epilepsy syndromes in humans. Although most studies have been focused on its function in the forebrain, ARX is also expressed in other regions of the developing nervous system including the floor plate (FP) of the spinal cord where its function is incompletely understood....
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