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Article

Unveiling cell surface and type IV secretion proteins responsible for archaeal rudivirus entry.

Journal of virology - 1 Sept 2014

Deng Ling, He Fei, Bhoobalan-Chitty Yuvaraj, Martinez-Alvarez Laura, Guo Yang, Peng Xu

Abstract excerpt

Sulfolobus mutants resistant to archaeal lytic virus Sulfolobus islandicus rod-shaped virus 2 (SIRV2) were isolated, and mutations were identified in two gene clusters, cluster sso3138 to sso3141 and cluster sso2386 and sso2387, encoding cell surface and type IV secretion proteins, respectively. The involvement of the mutations in the resistance was confirmed by genetic complementation. Blocking of virus entry...

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Identifiers

PMID: 24965447
DOI: 10.1128/JVI.01495-14
PMCID: PMC4136359

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