Article
Functional interplay between a virus and the ESCRT machinery in archaea.
Proceedings of the National Academy of Sciences of the United States of America - 25 Jun 2013
Snyder Jamie C, Samson Rachel Y, Brumfield Susan K, Bell Stephen D, Young Mark J
Abstract excerpt
Recently it has been discovered that a number of eukaryotic viruses, including HIV, coopt the cellular Endosomal Sorting Complex Required for Transport (ESCRT) machinery to affect egress from infected cells. Strikingly, the ESCRT apparatus is conserved in a subset of Archaea, including members of the genus Sulfolobus where it plays a role in cytokinesis. In the current work, we reveal that the archaeal virus...
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