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Development of a genetic system for the archaeal virus Sulfolobus turreted icosahedral virus (STIV).

Virology - 20 Jun 2011

Wirth Jennifer Fulton, Snyder Jamie C, Hochstein Rebecca A, Ortmann Alice C, Willits Deborah A, Douglas Trevor, Young Mark J

Abstract excerpt

Our understanding of archaeal viruses has been limited by the lack of genetic systems for examining viral function. We describe the construction of an infectious clone for the archaeal virus Sulfolobus turreted icosahedral virus (STIV). STIV was isolated from a high temperature (82°C) acidic (pH 2.2) hot spring in Yellowstone National Park and replicates in the archaeal model organism Sulfolobus solfataricus...

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PMID: 21496857
DOI: 10.1016/j.virol.2011.03.023

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