The Haemophilus influenzae sxy-1 mutation is in a newly identified gene essential for competence.

doi:10.1128/jb.176.22.6789-6794.1994

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Article

The Haemophilus influenzae sxy-1 mutation is in a newly identified gene essential for competence.

Journal of bacteriology - 1 Nov 1994

Williams P M, Bannister L A, Redfield R J

Abstract excerpt

The sxy-1 mutation of Haemophilus influenzae causes a 100- to 1,000-fold increase in spontaneous natural competence. We have used mapping and sequencing to identify this mutation as a G-to-A transition in an open reading frame adjacent to the rec-1 locus. This mutation substitutes valine for isol...

Topics

Alleles
Bacterial Proteins
Cyclic AMP
Genes, Bacterial
Haemophilus influenzae
Mutagenesis, Site-Directed
Mutation
Plasmids
Polymerase Chain Reaction
Restriction Mapping
Sequence Analysis, DNA
Transformation, Genetic

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