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Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding

31 May 2014

Abstract excerpt

// Akwasi Agyeman 1,* , Babal K Jha 1,* , Tapati Mazumdar 1 and Janet A Houghton 1 1 Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH Correspondence: Janet A. Houghton , email: // Keywords : Received : May 9, 2014 Accepted : May 30, 2014 Published : May 31, 2014 Abstract The GLI genes, GLI1 and GLI2, are transcription factors that regulate target genes at the distal end of...

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PMID: 24962990
DOI: 10.18632/oncotarget.2046

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