Ciliary biology: understanding the cellular and genetic basis of human ciliopathies.

Abstract excerpt

Motile cilia have long been known to play a role in processes such as cell locomotion and fluid movement whereas the functions of primary cilia have remained obscure until recent years. To date, ciliary dysfunction has been shown to be causally linked to a number of clinical manifestations that characterize the group of human disorders known as ciliopathies. This classification reflects a common or shared...

Topics

• Animals
• Cell Cycle
• Cilia
• Ciliary Motility Disorders
• Congenital Abnormalities
• Genetic Diseases, Inborn
• Hedgehog Proteins
• Humans
• Kidney Diseases, Cystic
• Mutation
• Obesity