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Article

Modest effects of lipid modifications on the structure of caveolin-3.

Biochemistry - 15 Jul 2014

Kim Ji-Hun, Peng Dungeng, Schlebach Jonathan P, Hadziselimovic Arina, Sanders Charles R

Abstract excerpt

Caveolin-3 (Cav3) is an unconventional membrane protein that serves as a critical scaffolding hub in caveolae and is genetically linked to various muscle disorders. In this work, we report the expression, purification, and characterization of full-length human Cav3. To mimic the palmitoylation of endogenous Cav3, we developed a generally applicable approach to covalently attached thioalkyl chains at natively...

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Identifiers

PMID: 24960539
DOI: 10.1021/bi5005238
PMCID: PMC4100780

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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