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Article

Differential effects of myopathy-associated caveolin-3 mutants on growth factor signaling.

The American journal of pathology - 1 Jul 2010

Brauers Eva, Dreier Agnes, Roos Andreas, Wormland Berthold, Weis Joachim, Krüttgen Alexander

Abstract excerpt

Caveolin-3 is an important scaffold protein of cholesterol-rich caveolae. Mutations of caveolin-3 cause hereditary myopathies that comprise remarkably different pathologies. Growth factor signaling plays an important role in muscle physiology; it is influenced by caveolins and cholesterol-rich rafts and might thus be affected by caveolin-3 dysfunction. Prompted by the observation of a marked chronic peripheral...

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Identifiers

PMID: 20472890
DOI: 10.2353/ajpath.2010.090741
PMCID: PMC2893669

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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