Article
Brain-specific knockdown of miR-29 results in neuronal cell death and ataxia in mice.
RNA (New York, N.Y.) - 1 Aug 2014
Roshan Reema, Shridhar Shruti, Sarangdhar Mayuresh A, Banik Arpita, Chawla Mrinal, Garg Manali, Singh Vijay P A L, Pillai Beena
Abstract excerpt
Several microRNAs have been implicated in neurogenesis, neuronal differentiation, neurodevelopment, and memory. Development of miRNA-based therapeutics, however, needs tools for effective miRNA modulation, tissue-specific delivery, and in vivo evidence of functional effects following the knockdow...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
