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Article

Genetic susceptibility of diffuse large B-cell lymphoma: a meta genome-wide association study in Asian population.

Leukemia - 1 Mar 2025

Cui Qian, Tan Wen, Song Bao, Peng Rou-Jun, Wang Ling, Dorajoo Rajkumar, Ng Kok Pin, Lin Guo-Wang, Au Wing-Yan, Liang Raymond H S, Khor Chiea Chuen, Zhang Qing-Ling, Foo Jia Nee, Li Sheng-Ping, Zhang Fu-Ren, Zhang Xue-Jun, Yu Xue-Qing, Lan Qing, Chanock Stephen, Jia Wei-Hua, Lim Soon Thye, Li Wen-Yu, Rothman Nathaniel, Bei Jin-Xin, Liu Jie, Lin Dongxin, Liu Jian-Jun

Abstract excerpt

Diffuse large B-cell lymphoma (DLBCL) is an aggressive malignancy and the most common form of non-Hodgkin lymphoma (NHL) that occurs worldwide. To discover risk factors and pathogenesis of DLBCL, we performed the largest GWAS of DLBCL to date in samples of East Asian ancestry, consisting of 2,888 patients with DLBCL and 12,458 controls. The meta-analysis identified three novel loci, rs2233434 on 6p21.1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lymphoma, Large B-Cell, Diffuse

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Source

Identifiers

PMID: 39707004
DOI: 10.1038/s41375-024-02503-4

Genes

ALDH2
BRAP
CD40
NFKBIE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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