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Article

Sensitive cell-based assay for determination of human immunodeficiency virus type 1 coreceptor tropism.

Journal of clinical microbiology - 1 May 2013

Weber Jan, Vazquez Ana C, Winner Dane, Gibson Richard M, Rhea Ariel M, Rose Justine D, Wylie Doug, Henry Kenneth, Wright Alison, King Kevin, Archer John, Poveda Eva, Soriano Vicente, Robertson David L, Olivo Paul D, Arts Eric J, Quiñones-Mateu Miguel E

Abstract excerpt

CCR5 antagonists are a powerful new class of antiretroviral drugs that require a companion assay to evaluate the presence of CXCR4-tropic (non-R5) viruses prior to use in human immunodeficiency virus (HIV)-infected individuals. In this study, we have developed, characterized, verified, and preval...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23486708
DOI: 10.1128/JCM.00092-13
PMCID: PMC3647936

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23486708-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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