Article
Cost-effectiveness and diagnostic effectiveness analyses of multiple algorithms for the diagnosis of Lynch syndrome.
Digestive diseases and sciences - 1 Dec 2014
Gould-Suarez Milena, El-Serag Hashem B, Musher Benjamin, Franco Luis Miguel, Chen Guoqing J
Abstract excerpt
BACKGROUND AND AIMS: The optimal algorithm to identify Lynch syndrome (LS) among patients with colorectal cancer (CRC) is unclear. The definitive test for LS, germline testing, is too expensive to be applied in all cases. Initial screening with the revised Bethesda Guidelines (RBG) cannot be applied in a considerable number of cases due to missing information. METHODS: We developed a model to evaluate the...
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