Article
Economic evaluation of genetic screening for Lynch syndrome in Germany.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Oct 2015
Severin Franziska, Stollenwerk Björn, Holinski-Feder Elke, Meyer Elisabeth, Heinemann Volker, Giessen-Jung Clemens, Rogowski Wolf
Abstract excerpt
PURPOSE: Lynch syndrome (LS) screening among patients with newly diagnosed colorectal cancer can decrease mortality in their affected first-degree relatives. In Germany, it is not yet clinical practice and the cost-effectiveness of different testing strategies is unknown. METHODS: We developed a decision-analytic model to analyze the cost-effectiveness of LS screening from the perspective of the German Statutory...
Topics
- Colorectal Neoplasms, Hereditary Nonpolyposis
- Cost-Benefit Analysis
- Decision Support Techniques
- Delivery of Health Care
- Early Detection of Cancer
- Genetic Testing
- Germany
- Heterozygote
- Humans
- Markov Chains
- Mutation
- Patient Acceptance of Health Care
- Precision Medicine