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Article

Strategies to identify the Lynch syndrome among patients with colorectal cancer: a cost-effectiveness analysis.

Annals of internal medicine - 19 Jul 2011

Ladabaum Uri, Wang Grace, Terdiman Jonathan, Blanco Amie, Kuppermann Miriam, Boland C Richard, Ford James, Elkin Elena, Phillips Kathryn A

Abstract excerpt

BACKGROUND: Testing has been advocated for all persons with newly diagnosed colorectal cancer to identify families with the Lynch syndrome, an autosomal dominant cancer-predisposition syndrome that is a paradigm for personalized medicine. OBJECTIVE: To estimate the effectiveness and cost-effectiveness of strategies to identify the Lynch syndrome, with attention to sex, age at screening, and differential effects...

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Source

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Identifiers

PMID: 21768580
DOI: 10.7326/0003-4819-155-2-201107190-00002
PMCID: PMC3793257

Genes

BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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Strategies to identify the Lynch syndrome among patients with colorectal cancer: a cost-effectiveness analysis.PMID 21768580Read ↗

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Recommendations from the EGAPP Working Group: genetic testing strategies in newly diagnosed individuals with colorectal cancer aimed at reducing morbidity and mortality from Lynch syndrome in relatives.Semantic proximity Read ↗

Economic evaluation of genetic screening for Lynch syndrome in Germany.Semantic proximity Read ↗

Economic Evaluation of Universal Lynch Syndrome Screening Protocols among Newly Diagnosed Patients with Colorectal CancerSemantic proximity Read ↗

Next-Generation Sequencing Panels for the Diagnosis of Colorectal Cancer and Polyposis Syndromes: A Cost-Effectiveness Analysis.Semantic proximity Read ↗

The cost-effectiveness of genetic testing strategies for Lynch syndrome among newly diagnosed patients with colorectal cancerSemantic proximity Read ↗

A cost-effectiveness analysis of prophylactic surgery versus gynecologic surveillance for women from hereditary non-polyposis colorectal cancer (HNPCC) Families.Semantic proximity Read ↗

Health benefits and cost-effectiveness of primary genetic screening for Lynch syndrome in the general population.Semantic proximity Read ↗

Cost-effectiveness and diagnostic effectiveness analyses of multiple algorithms for the diagnosis of Lynch syndrome.Semantic proximity Read ↗

Cost-effectiveness of population-wide genomic screening for Lynch Syndrome and polygenic risk scores to inform colorectal cancer screeningSemantic proximity Read ↗

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