Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oligogenic germline mutations identified in early non-smokers lung adenocarcinoma patients.

Lung cancer (Amsterdam, Netherlands) - 1 Aug 2014

Renieri Alessandra, Mencarelli Maria Antonietta, Cetta Francesco, Baldassarri Margherita, Mari Francesca, Furini Simone, Piu Pietro, Ariani Francesca, Dragani Tommaso A, Frullanti Elisa

Abstract excerpt

OBJECTIVES: A polygenic model is commonly assumed for the predisposition to common cancers. With respect to lung cancer, Genome Wide Association Studies (GWAS) have identified three loci at 15q25, 5p15.33, and 6p21. However, the relative risks associated with alleles at these loci are low; in add...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Adenocarcinoma of Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Age of Onset

Share to Computational Biology

Share to Germ-Line Mutation

Share to Neoplasm Staging

Share to Smoking

Source

Identifiers

PMID: 24954872
DOI: 10.1016/j.lungcan.2014.05.020

Genes

BAG6
EBLN2
JAK2
NELFE
NOP58
RBMX
SPEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24954872-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oligogenic germline mutations identified in early non-smokers lung adenocarcinoma patients.PMID 24954872Read ↗

Germline mutations in young non-smoking women with lung adenocarcinoma.Semantic proximity Read ↗

The Personalized Inherited Signature Predisposing to Non-small Cell Lung Cancer in Non-smokersSemantic proximity Read ↗

Inherited genetic risk factors in young-onset lung cancerSemantic proximity Read ↗

The role of germline mutations in non-small cell lung cancer: A systematic review of emerging genetic drivers and clinical implications.Semantic proximity Read ↗

Biological and therapeutic implications of the cancer-related germline mutation landscape in lung cancer.Semantic proximity Read ↗

Characteristics of genomic alterations of lung adenocarcinoma in young never-smokers.Semantic proximity Read ↗

Germline determinants of risk and molecular subtype in young-onset lung cancerSemantic proximity Read ↗

Identification of Germline Mutations in East-Asian Young Never-Smokers with Lung Adenocarcinoma by Whole-Exome SequencingSemantic proximity Read ↗

Lung Cancer: One Disease or Many.Semantic proximity Read ↗

Omic Approach in Non-smoker Female with Lung Squamous Cell Carcinoma Pinpoints to Germline Susceptibility and Personalized MedicineSemantic proximity Read ↗

Rare germline deleterious variants increase susceptibility for lung cancer.Semantic proximity Read ↗

Genomic Profiles of Pathogenic and Moderate-Penetrance Germline Variants Associated With Risk of Early-Onset Lung Adenocarcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.