Prevalence and characteristics of MUTYH-associated polyposis in patients with multiple adenomatous and serrated polyps.

doi:10.1158/1078-0432.CCR-13-1490

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Article

Prevalence and characteristics of MUTYH-associated polyposis in patients with multiple adenomatous and serrated polyps.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2014

Guarinos Carla, Juárez Miriam, Egoavil Cecilia, Rodríguez-Soler María, Pérez-Carbonell Lucía, Salas Ramón, Cubiella Joaquín, Rodríguez-Moranta Francisco, de-Castro Luisa, Bujanda Luis, Serradesanferm Anna, Nicolás-Pérez David, Herráiz Maite, Fernández-Bañares Fernando, Herreros-de-Tejada Alberto, Aguirre Elena, Balmaña Judith, Rincón María-Luisa, Pizarro Angeles, Polo-Ortiz Francisco, Castillejo Adela, Alenda Cristina, Payá Artemio, Soto José-Luis, Jover Rodrigo

Abstract excerpt

PURPOSE: The present study aimed to determine the prevalence of MUTYH mutations in patients with multiple colonic polyps and to explore the best strategy for diagnosing MUTYH-associated polyposis (MAP) in these patients. EXPERIMENTAL DESIGN: This study included 405 patients with at least 10 colonic polyps each. All cases were genetically tested for the three most frequent MUTYH mutations. Whole-gene analysis was...

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Identifiers

PMID: 24470512
DOI: 10.1158/1078-0432.CCR-13-1490

Genes

MUTYH
BRAF
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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