Article
Dominance effects of deleterious and beneficial mutations in a single gene of the RNA virus ϕ6.
PloS one - 1 Jan 2014
Joseph Sarah B, Peck Kayla M, Burch Christina L
Abstract excerpt
Most of our knowledge of dominance stems from studies of deleterious mutations. From these studies we know that most deleterious mutations are recessive, and that this recessivity arises from a hyperbolic relationship between protein function (i.e., protein concentration or activity) and fitness. Here we investigate whether this knowledge can be used to make predictions about the dominance of beneficial and...
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