Test of synergistic interactions among deleterious mutations in bacteria.

doi:10.1038/37108

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Article

Test of synergistic interactions among deleterious mutations in bacteria.

Nature - 27 Nov 1997

Elena S F, Lenski R E

Abstract excerpt

Identifying the forces responsible for the origin and maintenance of sexuality remains one of the greatest unsolved problems in biology. The mutational deterministic hypothesis postulates that sex is an adaptation that allows deleterious mutations to be purged from the genome; it requires synergi...

Topics

Directed Molecular Evolution
Escherichia coli
Genes, Bacterial
Genotype
Models, Genetic
Mutagenesis, Insertional
Mutation
Recombination, Genetic
Sex

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