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Article

Intermediate CGG repeat length at the FMR1 locus is not associated with hormonal indicators of ovarian age.

Menopause (New York, N.Y.) - 1 Jul 2014

Kline Jennie K, Kinney Ann M, Levin Bruce, Brown Stephen A, Hadd Andrew G, Warburton Dorothy

Abstract excerpt

OBJECTIVE: Premutation and intermediate CGG repeat length at the fragile X mental retardation 1 (FMR1) locus have been associated with premature ovarian failure. We tested whether intermediate length is associated with indicators of ovarian age in a sample of fertile women. Our primary measures of ovarian age were antimüllerian hormone (AMH) and follicle-stimulating hormone (FSH) levels. METHODS: The...

Topics

Abortion, Spontaneous
Adult
Alleles
Anti-Mullerian Hormone
Chromosome Mapping
Female
Follicle Stimulating Hormone
Fragile X Mental Retardation Protein
Genotype
Humans
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pregnancy

Primary Ovarian Insufficiency

Trinucleotide Repeat Expansion

Trisomy

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 24423935
DOI: 10.1097/GME.0000000000000139
PMCID: PMC4065625

Genes

AMH
FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Intermediate CGG repeat length at the FMR1 locus is not associated with hormonal indicators of ovarian age.PMID 24423935Read ↗

Intermediate sized CGG repeats are not a common cause of idiopathic premature ovarian failure.Semantic proximity Read ↗

AMH in women with diminished ovarian reserve: potential differences by FMR1 CGG repeat level.Semantic proximity Read ↗

Diminished ovarian reserve is not observed in infertility patients with high normal CGG repeats on the fragile X mental retardation 1 (FMR1) geneSemantic proximity Read ↗

Trisomic pregnancy and intermediate CGG repeat length at the FMR1 locus.Semantic proximity Read ↗

The significance of fragile X mental retardation gene 1 CGG repeat sizes in the normal and intermediate range in women with primary ovarian insufficiency.Semantic proximity Read ↗

Correlation of normal-range FMR1 repeat length or genotypes and reproductive parameters.Semantic proximity Read ↗

FMR1 allelic complexity in premutation carriers provides no evidence for a correlation with age at amenorrhea.Semantic proximity Read ↗

FMR1 gene CGG repeat variation within the normal range is not predictive of ovarian response in IVF cycles.Semantic proximity Read ↗

Early decline in functional ovarian reserve in young women with low (CGGn < 26) FMR1 gene alleles.Semantic proximity Read ↗

Length of FMR1 repeat alleles within the normal range does not substantially affect the risk of early menopause.Semantic proximity Read ↗

Reproductive and gynecologic care of women with fragile X primary ovarian insufficiency (FXPOI).Semantic proximity Read ↗

Low and High-Normal FMR1 Triplet Cytosine, Guanine Guanine Repeats Affect Ovarian Reserve and Fertility in Women Who Underwent In Vitro Fertilization Treatment? Results from a Cross-Sectional Study.Semantic proximity Read ↗

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