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Article

FMR1 and the continuum of primary ovarian insufficiency.

Seminars in reproductive medicine - 1 Jul 2011

Sullivan Shannon D, Welt Corrine, Sherman Stephanie

Abstract excerpt

Spontaneous 46,XX primary ovarian insufficiency (POI) is a term that describes ovarian dysfunction resulting in a range of abnormalities, from infertility to early menopause as the end stage (overt POI). The most common known genetic cause of 46,XX POI is the expansion of a CGG repeat to 55 to 199 copies in the 5' untranslated region in the X-linked FMR1 gene. This "premutation" is associated with overt POI...

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Source

Identifiers

PMID: 21969264
DOI: 10.1055/s-0031-1280915

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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