Article
Robust clinical outcome prediction based on Bayesian analysis of transcriptional profiles and prior causal networks.
Bioinformatics (Oxford, England) - 15 Jun 2014
Zarringhalam Kourosh, Enayetallah Ahmed, Reddy Padmalatha, Ziemek Daniel
Abstract excerpt
MOTIVATION: Understanding and predicting an individual's response in a clinical trial is the key to better treatments and cost-: effective medicine. Over the coming years, more and more large-scale omics datasets will become available to characterize patients with complex and heterogeneous diseases at a molecular level. Unfortunately, genetic, phenotypical and environmental variation is much higher in a human...
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