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Article

A biological network-based regularized artificial neural network model for robust phenotype prediction from gene expression data.

BMC bioinformatics - 19 Dec 2017

Kang Tianyu, Ding Wei, Zhang Luoyan, Ziemek Daniel, Zarringhalam Kourosh

Abstract excerpt

BACKGROUND: Stratification of patient subpopulations that respond favorably to treatment or experience and adverse reaction is an essential step toward development of new personalized therapies and diagnostics. It is currently feasible to generate omic-scale biological measurements for all patients in a study, providing an opportunity for machine learning models to identify molecular markers for disease diagnosis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29258445
DOI: 10.1186/s12859-017-1984-2
PMCID: PMC5735940

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