Article
Pre-activated blood platelets and a pro-thrombotic phenotype in APP23 mice modeling Alzheimer's disease.
Cellular signalling - 1 Sept 2014
Jarre Andrea, Gowert Nina S, Donner Lili, Münzer Patrick, Klier Meike, Borst Oliver, Schaller Martin, Lang Florian, Korth Carsten, Elvers Margitta
Abstract excerpt
Platelet activation and thrombus formation play a critical role in primary hemostasis but also represent a pathophysiological mechanism leading to acute thrombotic vascular occlusions. Besides, platelets modulate cellular processes including inflammation, angiogenesis and neurodegeneration. On th...
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