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Article

Association of 24 bp duplication of human CHIT1 gene with asthma in a heterozygous population of north India: a case-control study.

Lung - 1 Oct 2014

Sinha Shweta, Singh Jagtar, Jindal Surinder Kumar, Birbian Niti, Singla Neha

Abstract excerpt

PURPOSE: CHIT1 is expressed by pulmonary macrophages, which is typically the site of entry for many environmental fungi that may increase the risk of pulmonary fungal infection and lead to hypersensitivity. The conserved expression of this gene in humans suggests its physiological importance in the mammalian lung. METHODS: The present study was conducted with a total of 964 subjects, including 483 healthy...

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Identifiers

PMID: 24928104
DOI: 10.1007/s00408-014-9605-6

Genes

CHIT1

Provenance

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