Article
Dense genotyping of immune-related loci identifies variants associated with clearance of HPV among HIV-positive women in the HIV epidemiology research study (HERS).
PloS one - 1 Jan 2014
Sudenga Staci L, Wiener Howard W, King Caroline C, Rompalo Anne M, Cu-Uvin Susan, Klein Robert S, Shah Keerti V, Sobel Jack D, Jamieson Denise J, Shrestha Sadeep
Abstract excerpt
Persistent high-risk human papillomavirus (HR-HPV) is a necessary and causal factor of cervical cancer. Most women naturally clear HPV infections; however, the biological mechanisms related to HPV pathogenesis have not been clearly elucidated. Host genetic factors that specifically regulate immune response could play an important role. All HIV-positive women in the HIV Epidemiology Research Study (HERS) with a...
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