Human papillomavirus sequencing reveals its usefulness for the management of HIV-infected women at risk for developing cervical cancer.

doi:10.1111/jog.14754

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Article

Human papillomavirus sequencing reveals its usefulness for the management of HIV-infected women at risk for developing cervical cancer.

The journal of obstetrics and gynaecology research - 1 Jun 2021

Piyathilake Chandrika J, Kumar Ranjit, Crowley Michael R, Badiga Suguna, Burkholder Greer A

Abstract excerpt

AIM: Next-generation sequencing (NGS) is able to describe the composition of human papillomaviruses (HPVs) as percent (%) reads rather than positive/negative results. Therefore, we used this unique approach to assess the prevalence of cervical HPVs of HIV infected (HIV+) in order to understand the determinants of being infected with higher % reads of high risk (HR)-HPVs and cervical abnormalities of atypical...

Topics

Alphapapillomavirus
Female
Genotype
HIV Infections
Human papillomavirus 16
Human papillomavirus 18
Humans
Papillomaviridae
Papillomavirus Infections
Uterine Cervical Neoplasms

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Open in PubMed

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PMID: 33754434
DOI: 10.1111/jog.14754

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