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Article

Free fatty acid uptake in humans with CD36 deficiency.

Diabetes - 1 Nov 2014

Hames Kazanna C, Vella Adrian, Kemp Bradley J, Jensen Michael D

Abstract excerpt

Animal models have demonstrated that CD36 facilitates cell membrane free fatty acid (FFA) transport, but its role in human metabolism is not well understood. We measured heart, liver, adipose (three depots), and muscle (truncal postural and thigh locomotive) FFA uptake using [(11)C]palmitate positron emission tomography (PET) scans in a family of five carrying the Pro90Ser CD36 mutation (2 homozygotes had no...

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Identifiers

PMID: 24917573
DOI: 10.2337/db14-0369
PMCID: PMC4207394

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