Article
Attenuated aerobic exercise capacity in CD36 deficiency.
Journal of medical genetics - 1 Jul 2007
Yanai Hidekatsu, Watanabe Ichiro, Ishii Kojiro, Morimoto Mie, Fujiwara Hironobu, Yoshida Shigeru, Hui Shu-Ping, Matsuno Kazuhiko, Chiba Hitoshi
Abstract excerpt
BACKGROUND: An important role of CD36 in muscle fatty acid (FA) uptake has been shown in CD36-knockout or CD36-overexpressed mice. FA is a predominant substrate in energy production during light exercise below the anaerobic threshold (AT). We studied whether aerobic exercise capacity in humans could be affected by CD36 deficiency. METHODS: We investigated the ventilatory threshold (VT) and serum FA changes in...
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