Article
CD36 genotype and long-chain fatty acid uptake in the heart.
Circulation journal : official journal of the Japanese Circulation Society - 1 Sept 2002
Kintaka Taigo, Tanaka Takao, Imai Makoto, Adachi Itaru, Narabayashi Isamu, Kitaura Yasushi
Abstract excerpt
Homozygous or compound heterozygous mutation of the CD36 gene (CD36-/-) in humans results in severe defects of the uptake of long-chain fatty acids (LCFAs) in the heart. Because the effect of a single mutation of this gene (CD36+/-) on the LCFA uptake is not known, it was evaluated in 29 subjects with the CD36 wild-type gene (WT) (6 healthy subjects, 10 patients with heart disease), CD36+/- (4 healthy subjects, 5...
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