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Article

Single aromatic residue location alters nucleic acid binding and chaperone function of FIV nucleocapsid protein.

Virus research - 26 Nov 2014

Wu Hao, Wang Wei, Naiyer Nada, Fichtenbaum Eric, Qualley Dominic F, McCauley Micah J, Gorelick Robert J, Rouzina Ioulia, Musier-Forsyth Karin, Williams Mark C

Abstract excerpt

Feline immunodeficiency virus (FIV) is a retrovirus that infects domestic cats, and is an excellent animal model for human immunodeficiency virus type 1 (HIV-1) pathogenesis. The nucleocapsid (NC) protein is critical for replication in both retroviruses. FIV NC has several structural features that differ from HIV-1 NC. While both NC proteins have a single conserved aromatic residue in each of the two zinc...

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Identifiers

PMID: 24915282
DOI: 10.1016/j.virusres.2014.06.002
PMCID: PMC4252577

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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